Volume 01, Issue-1, December 2023

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Evaluation of antioxidant, anti-arthritic and anthelmintic activities of methanolic leaves extract of Chaetocarpus castanocarpus (Roxb.)
(CRP, International Islamic University Chittagong, 2023-12) Khatun, Mst. Riniara
(Roxb.) leaves (MECCL). Phytochemical screenings were performed by using standard protocols. MECCL demonstrated solid free radical scavenging activity in DPPH (1, 1-diphenyl- 2-picrylhydrazyl) test, as well as total phenol and total flavonoid content were found in a quantitative assay. The topmost value of antioxidant potency (87.38%) of MECCL has exposed at 500 μg/ml concentration, whereas standard ascorbic acid reveals a 97.49% outcome at an identical concentration. However, the flavonoid and phenolic potentials of MECCL were found at 149.14± 0.084 mg QE/gm and 184.66 ± 0.064 mg GAE/gm, correspondingly. The in vitro anti-arthritic activity was appraised by protein denaturation method, whereas plant extracts proclaimed dose-dependent response working on protein denaturation method and the peak inhibition was found (60.32 ± 1.72) at 500 μg/mL concentration. MECCL also proclaimed the dose-related anthelmintic activity on aquarium worm (Tubifex tubifex) as revealed by the decreased paralyzing time and death time. So, the current research propose that Chaetocarpus castanocarpus (Roxb.) could be a better choice for managing cardiovascular disease, arthritis and helminthiasis .