Antimicrobial potentials of leaves of Syzygium fruticosum (Roxb.)

Abstract

The study was designed to investigate the antimicrobial principles of Sygygium fruticosum (Roxb.). The methanolic extract (CME) of leaves of S. fruticosum was successively fractionated with different organic solvents such as petroleum ether (PEF), chloroform (CHF) and ethyl acetate (EAF) to get four fractions: PEF, CHF, EAF and aqueous fraction (AQF). The antibacterial potentials of the extractives were determined using the agar well diffusion method against Bacillus cereus, Stephylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Shigella boydii, and Shigella sonnei. The dilution method was used to calculate the minimum inhibitory concentration (MIC). The antibacterial activity of extractives was mild to moderate level against experimental bacterial strains. Among the extractives, EAF had the highest antibacterial efficacy against bacterial strains. The EAF's MIC value of 32 g/ml indicated that it might be employed as a powerful antibacterial agent.